Mounjaro vs. Wegovy: Which One is Right for You?

If you’re considering medical weight loss in 2026, you’ve likely come across two names: Wegovy and Mounjaro. Both are highly effective, once-weekly injections licensed in the UK, but they aren't identical.

We often get asked: "Which one is better?" The answer depends on your health goals, your budget, and how your body responds to treatment. Here is a breakdown of how they compare.

1. The Science: How Do They Work?

While both medications help you feel fuller for longer and reduce "food noise," they target different pathways in the body:

• Wegovy (Semaglutide): Mimics one hormone, GLP-1. This hormone slows down your stomach emptying and tells your brain you’re full.

  
  
  
  

• Mounjaro (Tirzepatide): Is a "dual-agonist," meaning it mimics two hormones—GLP-1 and GIP. This second hormone (GIP) is thought to further enhance how your body breaks down fat and sugar, potentially offering a more powerful metabolic boost.

  
  
  
  

2. Effectiveness: What the Research Says

Both medications deliver life-changing results, but Mounjaro currently holds a slight edge in clinical trials:

• Mounjaro: At the highest 15mg dose, patients lost an average of 20.9% of their body weight over 72 weeks.

  
  

• Wegovy: Traditionally, Wegovy (2.4mg) saw results of around 15-17%. However, with the newly approved 7.2mg dose available in 2026, Wegovy has narrowed the gap significantly, with average weight loss now reaching 20.7%.

  
  
  
  

3. Side Effects and Tolerability

Because they work in similar ways, they share similar side effects—mostly related to the digestive system (nausea, heartburn, or changes in bowel habits).

• Wegovy has a slightly longer safety track record and is often preferred by patients who want a well-established treatment with recognized cardiovascular benefits.

  
  

• Mounjaro is highly effective, but because it targets two receptors, some patients find the "step up" in doses more noticeable.

  
  

4. Pricing and Value (March 2026)

At Brook Aesthetics, we believe in transparent pricing. Following the recent manufacturer price hikes, here is how the 2026 market looks:

Feature	Wegovy	Mounjaro
Typical Monthly Cost	From £140	From £190 (Rising with dose)
Maintenance Dose	2.4mg or 7.2mg	5mg, 10mg, or 15mg
Best For	Cardiovascluar health & affordability	Maximum weight loss results

The "Brook Aesthetics" Difference

Choosing between these two isn't something you should do alone. Unlike online "subscription" pharmacies that simply post a box, we provide a face-to-face clinical service in Lisburn. During your consultation, we look at your medical history, your BMI, and your lifestyle to recommend the pen that fits you best. We also provide the vital health checks—like blood pressure and weight monitoring—that ensure your journey is safe.

Comparison Summary:

• Choose Wegovy if: You are looking for a more cost-effective entry point or have a history of heart health concerns.

  
  

• Choose Mounjaro if: You have struggled with "weight loss plateaus" in the past and want the most powerful metabolic tool currently available.

Ready to find your perfect fit? [Book your consultation at our Lisburn clinic today] and let's start your journey together.